Understanding interaction (subgroup) analysis in randomised studies

When we try to interpret findings from a study, we often like to understand whether an effect (of a treatment or test condition) might be different in subjects with different characteristics. If there was substantial variability among subjects, this may have masked a treatment effect in a select few. How can we understand effects in select groups of subjects that

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Licensing data and code on the Open Science Foundation

Research funders are beginning to require that data produced in the course of the research they fund should be made openly available. This is to encourage further discovery and exploration, as well as to extend research questions. In addition, releasing data and code can be in researchers’ interest because it provides a complete and transparent record of how the conclusions

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Why we need to report more than “Data were analysed by t-tests or ANOVA”

T-tests and analysis of variance (ANOVA) are common statistical tests in physiology and biomedical science. While the SAMPL guidelines for reporting statistical analyses and methods in published literature state authors should “describe statistical methods with enough detail to enable a knowledgeable reader with access to the original data to verify the reported results”, such recommendations are rarely implemented. Simply stating

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